Bet 440

Duration 4 years (02008-02012)

“By 2012, current venture capital- and privately-funded methods of DNA sequencing, independent of any additional “incremental improvements” will be made obsolete by the technology described in The Economist (October 25th - 31st 2008; US print edition, p.82) and at http://www.5bases.com.”

PREDICTOR
Lux Veritas

CHALLENGER
Unchallenged

Veritas's Argument

All existing DNA sequencing methods are intrinsically at least one million times slower and at least one thousand times more expensive per complete human genome than the direct physical method of DNA sequencing that was hinted in The Economist advertisement (October 25th - 31st 2008; US print edition, p.82).

Identification of individual molecules from arbitrary complexity in up to Terahertz speed, as claimed in The Economist translates into sequencing a single human genome in a fraction of a second (quicker than the blink of an eye).

Non-physical DNA sequencing techniques, regardless of the level of multiplexing cannot accomplish such a rate economically. This fundamental physical limit is currently not understood as an intrinsic limitation by the proponents of DNA sequencing-by-synthesis and other non-direct and non-physical DNA sequencing paradigms. The unfair advantage of the DNA sequencing method advertised in The Economist by means of advanced nano-photonics is the Terahertz speed of identifying molecules from arbitrary complexity.

Using such a purely physical method enables sequencing an arbitrary number of people, who will obtain their genome sequence as effortlessly as making an online bank transaction.

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